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CD20loCD19+ B cells from B-CLL patients suppress T cells
| Patients | Compared to ND | Rituximab | ||
|---|---|---|---|---|
| CD20 decrease * | Suppression | 4-1BBL | ||
| 1 | + | +++ | Low | + |
| − | − | Low | − | |
| 2 | − | − | ND | − |
| − | − | ND | − | |
| 3 | + | +++ | Low | + |
| 4 | + | ++ | Low | − |
| 5 | + | ++ | Low | − |
| 6 | + | ++ | Equal | + |
| 7 | + | + | ND | + |
| 8 | + | + | High | − |
| 9 | − | − | Equal | − |
| 10 | − | − | High | − |
| 11 | − | − | Equal | − |
| 12 | − | + | Low | + |
| 13 | + | ++ | low | + |
CD19+ B cells from B-CLL patients were phenotyped for CD20 and 4-1BBL expression and tested for T cell suppression
+ corresponds to > 40% decrease compared to ND
