Figure 1.

Subject-specific head modeling. (A) T1-weighted MRI volume. (B) Segmented head volume displaying scalp, skull, CSF, gray matter and white matter. (C) High-density tetrahedral mesh for finite element forward light model. (D) Optode positions localized on mesh. The high-density optode grid is composed of 24 sources (red) and 28 detectors (blue). (E) Surface rendering of cortex. Yellow coloring denotes FOV of HD-DOT imaging pad derived from top 50% of the summed sensitivity matrix (see Methods) on the cortical ribbon of Subject 2.