Figure 3. [3H](R)-PK11195 autoradiography overlaps mainly with CD68 labeled activated microglia/macrophages.

Combined autoradiography with [3H](R)-PK11195 and immunostaining was performed on a frozen brain section obtained from the frontal cortex of a patient with AD. Immunostaining was performed for astrocytes (GFAP, red) and activated microglia/macrophages (CD68, green). [3H](R)-PK11195 specific binding (black grains) overlapped mainly with CD68 labeled activated microglia/macrophages (merge).