Fig. 6.
Enhancing effects of EB administration to OVX mice on performance of the object-placement task. Each experimental and control group consisted of 10 OVX mice. All tests were conducted 24 h after injection of the last EB. EB was administered 1 μg/day for 5 days in the object-placement test. The delay between sampling the objects and the memory tests was 30 min. *, Statistically significant differences (ANOVA with paired t test). Oil-treated mice (OVX+Oil) could no longer discriminate old vs. new locations (P > 0.05), whereas EB-treated mice (OVX+EB) spent significantly more time with the new locations (P < 0.01), indicating that they still remembered the spatial locations.