Fig. 2.
Delivery performance depends on cell speed and constriction design. Constriction dimensions (Fig. S1) are denoted by numbers (e.g., 10 μm − 6 μm × 5) such that the first number corresponds to constriction length, the second to constriction width and the third (if present) to the number of constrictions in series per channel. (A) Delivery efficiency and (B) cell viability 18 h after treatment as a function of cell speed for 40 μm − 6 μm (○), 20 μm − 6 μm (□), and 10 μm − 6 μm × 5 (∆) device designs. Efficiencies and viabilities were measured by flow cytometry after propidium iodide staining. For information regarding cell recovery rates, refer to SI Note S1. All data points were run in triplicate, and error bars represent 2 SDs.