Figure 1. Global spatiotemporal dynamics of gene expression.
a, Venn diagrams representing total number of genes considered to expressed and the number of spatially and temporally DEX genes for brain regions (top) and NCX areas (bottom). b, MDS plot showing transcriptional similarity, colored by periods (top) and regions (bottom). Euclidean distance of log2-transformed signal intensity (nonmetric, stress=18.9%) was used to measure pairwise similarity. c, Heat map matrix of pairwise Spearman correlations between brain regions (top) or NCX areas (bottom) during fetal development (periods 3–7), postnatal development (periods 8–12), and adulthood (periods 13–15).
