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. 2012 Nov 20;108(1):155–162. doi: 10.1038/bjc.2012.524

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Copyright © 2013 Cancer Research UK

From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Association of FOXP3⁺ TIL with patient survival. (A) Representative immunohistochemical staining of FOXP3 (brown nuclei), with examples of intraepithelial (arrowhead) and stromal (arrows) FOXP3⁺ TIL. Original magnification, × 200. (B) Box plots representing FOXP3⁺ TIL levels among tumour epithelia and stroma. (C) Distribution of FOXP3⁺ TIL in cases with (n=93) or without (n=82) disease recurrence at final follow-up. (D) Association of FOXP3⁺ TIL with RFS in the training, validation, and combined cohorts (FOXP3 high, n=92; FOXP3 low, n=83).