. Author manuscript; available in PMC: 2014 Feb 1.

Published in final edited form as: Alcohol. 2012 Nov 28;47(1):10.1016/j.alcohol.2012.11.001. doi: 10.1016/j.alcohol.2012.11.001

TABLE 1.

DALA, DAMGO, U-50,488H, and m-naloxone injected 2.0 mm dorsal to the target area produced no change in ethanol, food, or water intake, showing that effects were region-specific.

Nutrient	Hour 1	Hour 2	Hour 4
Ethanol (g/kg)
Vehicle	0.17 ± 0.03	0.36 ± 0.07	0.54 ± 0.09
DALA 7.1 nmol	0.17 ± 0.03	0.35 ± 0.08	0.53 ± 0.10
Food (g)
Vehicle	9.40 ± 0.94	10.68 ± 0.78	17.73 ± 1.28
DALA 7.1 nmol	10.13 ± 0.75	10.99 ± 0.62	18.19 ± 0.83
Water (ml)
Vehicle	9.41 ± 0.62	12.85 ± 1.01	22.31 ± 1.15
DALA 7.1 nmol	10.26 ± 0.48	12.79 ± 0.57	23.40 ± 0.66

Ethanol (g/kg)
Vehicle	0.43 ± 0.10	0.85 ± 0.21	1.30 ± 0.32
DAMGO 2.9 nmol	0.30 ± 0.09	0.56 ± 0.15	1.06 ± 0.34
Food (g)
Vehicle	9.91 ± 1.78	11.54 ± 2.17	17.46 ± 2.39
DAMGO 2.9 nmol	8.66 ± 0.72	10.24 ± 1.12	15.23 ± 1.13
Water (ml)
Vehicle	3.83 ± 1.52	6.04 ± 2.01	11.43 ± 4.10
DAMGO 2.9 nmol	5.64 ± 1.75	8.06 ± 2.20	13.03 ± 3.74

Ethanol (g/kg)
Vehicle	0.21 ± 0.04	0.41 ± 0.10	0.63 ± 0.22
U-50,488H 5.4 nmol	0.14 ± 0.04	0.28 ± 0.06	0.43 ± 0.09
Food (g)
Vehicle	9.94 ± 1.14	10.88 ± 0.83	15.12 ± 1.58
U-50,488H 5.4 nmol	9.86 ± 0.96	10.60 ± 0.61	15.46 ± 0.87
Water (ml)
Vehicle	6.80 ± 1.21	10.80 ± 1.19	17.60 ± 2.67
U-50,488H 5.4 nmol	7.22 ± 0.46	12.10 ± 1.04	20.74 ± 0.90

Ethanol (g/kg)
Vehicle	0.23 ± 0.03	0.38 ± 0.03	0.60 ± 0.05
m-Naloxone 2.1 nmol	0.21 ± 0.05	0.40 ± 0.08	0.55 ± 0.08
Food (g)
Vehicle	9.47 ± 0.48	11.45 ± 0.72	15.78 ± 0.39
m-Naloxone 2.1 nmol	8.70 ± 0.84	11.52 ± 0.16	16.25 ± 0.66
Water (ml)
Vehicle	7.52 ± 1.16	12.65 ± 1.22	20.22 ± 1.57
m-Naloxone 2.1 nmol	7.22 ± 0.89	12.50 ± 0.60	19.63 ± 0.94

Values are mean ± S.E.M.. DALA: n = 8/group; DAMGO: n = 7/group; U-50,488H: n = 5/group; m-Naloxone: n = 6/group.