Figure 2. Somatic mutations in whole genome sequenced AMKL cases.
Plots depict structural genetic variants, including DNA copy number alterations, intraand inter-chromosomal translocations, and sequence alterations (Krzywinski et al., 2009). DNA copy number alterations: Loss of heterozygosity (LOH), orange; amplification, red; deletion, blue. Sequence mutations in Refseq genes: silent single nucleotide variants (SNVs), black; UTR, brown; non-silent SNVs, blue. Genes at structural variant breakpoints: genes involved in in-frame fusions, red; others, green.
