FIG. 6.
Illness and virus clearance in mice with delayed anti-LFA-1 treatment during primary RSV infection. Mice were infected as previously described. On days +5, +7, and +10 relative to infection, 200 μg of isotype control antibody or anti-LFA-1 antibody was administered to mice intraperitoneally. (A) Data representing the mean percent weight loss ± the standard deviation for six mice. (B) Virus titers are represented as the log10 PFU per gram of lung ± the standard deviation for mice that were subjected to the same treatment regimen as those for which results are shown in panel A. Five mice are represented at each time point. The limit of detection is 1.8 log10 PFU/g. For day 8, P is >0.05.