Figure 2.
Transpososome structure. The complex sits on a crystallographic twofold (vertical) that relates the blue and red halves. The pale- and dark-colored subunits adopt different conformations within the homotetramer. DNA colors match Figure 1. a) Cartoon. Catalytic sites are marked as yellow and tan stars (facing the viewer or the background, respectively) and domains of the blue subunits are labeled. b) Ribbon drawing, with the scissile phosphate groups shown as yellow spheres. c) Same drawing as in B, rotated ~90° about a vertical axis.