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Model of V-ATPase structure and reversible disassembly: A. Model of V-ATPase subunit composition and structure; an estimate of stoichiometry based on Ref. [27] is shown. V1 subunits are designated in upper case and Vo subunits are indicated in lower case.. B. Diagram of reversible disassembly in response to glucose deprivation and readdition. The C subunit is released from both sectors upon disassembly.
