Figure 2.
(A) Experimental box at the time of the Go stimulus and (B) performance of a correct trial in the memory-guided task. (C) A rat in the stimulus-guided task, in which a light inside one of the reward ports indicated the location for a correct head entry after a lever press. (D) Spread of 2 μL injections of the dye Pontamine sky blue into the mPFC of an untrained rat, shown over a series of ~50 μm thick sections. The center of the infusion in the left hemisphere is shown in the left brain section. The center of the infusion in the right hemisphere is shown in the right brain section. The center image was located between the two infusion sites. Note that the dye was retained within the medial prefrontal cortex. (E) Locations of infusion sites based on reconstructions of tissue dispersion patterns (shown as gray shaded areas) at the end of the tracks made by the guide cannula. In each rat, the cannula ended within the medial prefrontal cortex (Cg1/PrL areas). (Images are based on Paxinos and Watson, 1998).