Table 2. Individual and mean±SD 18F-DPA-714 DVR values obtained for the 8 healthy controls and the 10 ALS patients and results of Mann-Whitney test.
| Subject | Primary Motor | SupplementaryMotor | Temporal | Occipital | Frontal | Thalamus | Cerebellum | Pons |
| Controls | ||||||||
| HC1 | 1.26 | 1.15 | 1.18 | 1.16 | 1.41 | 1.57 | 1.09 | 1.81 |
| HC2 | 0.99 | 1.09 | 0.97 | 0.98 | 1.07 | 1.22 | 1.02 | 1.61 |
| HC3 | 1.08 | 1.18 | 1.16 | 1.03 | 1.17 | 1.48 | 1.11 | 1.76 |
| HC4 | 0.96 | 1.00 | 0.98 | 1.04 | 1.03 | 1.31 | 0.95 | 1.52 |
| HC5 | 0.98 | 0.96 | 1.04 | 1.04 | 0.99 | 1.25 | 1.11 | 1.56 |
| HC6 | 0.85 | 0.97 | 0.91 | 0.99 | 0.85 | 1.18 | 0.97 | 1.36 |
| HC7 | 0.99 | 1.09 | 1.06 | 1.00 | 0.97 | 1.40 | 1.16 | 1.84 |
| HC8 | 1.05 | 1.09 | 1.12 | 1.01 | 1.18 | 1.43 | 1.09 | 1.75 |
| Mean | 1.02 | 1.07 | 1.05 | 1.03 | 1.08 | 1.35 | 1.06 | 1.65 |
| SD | 0.12 | 0.08 | 0.10 | 0.06 | 0.17 | 0.14 | 0.08 | 0.16 |
| ALS patients | ||||||||
| Bulbar onset | ||||||||
| ALS1 | 1.12 | 1.25 | 1.16 | 0.96 | 1.24 | 1.38 | 0.99 | 1.65 |
| ALS2 | 1.24 | 1.24 | 1.23 | 1.11 | 1.12 | 1.53 | 1.09 | 1.65 |
| ALS3 | 1.17 | 1.19 | 1.12 | 1.03 | 1.02 | 1.30 | 0.98 | 1.58 |
| ALS5 | 1.23 | 1.24 | 1.24 | 1.12 | 1.18 | 1.52 | 1.11 | 1.81 |
| ALS6 | 1.23 | 1.24 | 1.28 | 1.10 | 1.36 | 1.55 | 1.18 | 1.64 |
| ALS9 | 1.19 | 1.29 | 1.17 | 1.11 | 1.11 | 1.54 | 1.27 | 1.68 |
| Spinal onset | ||||||||
| ALS4 | 1.08 | 1.23 | 1.24 | 1.09 | 1.13 | 1.58 | 1.14 | 1.63 |
| ALS7 | 1.02 | 1.03 | 1.06 | 1.00 | 1.04 | 1.20 | 1.05 | 1.35 |
| ALS8 | 1.07 | 1.10 | 1.09 | 1.03 | 1.08 | 1.41 | 1.14 | 1.52 |
| ALS10 | 1.09 | 1.29 | 1.24 | 1.08 | 1.16 | 1.56 | 1.13 | 1.76 |
| Mean | 1.14 | 1.21 | 1.18 | 1.06 | 1.14 | 1.46 | 1.11 | 1.63 |
| SD | 0.08 | 0.08 | 0.07 | 0.05 | 0.10 | 0.13 | 0.09 | 0.12 |
| Wilcoxon-test (p value) | 0.009 | 0.001 | 0.004 | 0.155 | 0.197 | 0.0563 | 0.096 | 0.376 |
DVR: Distribution of volume ratios -SD: Standard deviation.
Mann-Whitney-test: comparison between HC subjects (n = 8) and ALS patients (n = 10).