Figure 2. Age-dependent lymphadenopathy of G3KO mice.
A. A photo of inguinal lymph nodes from 6 week-old FF and G3KO mice. B. Absolutes numbers of lymph node cells, CD8+ T cells, and B cells per inguinal lymph node from FF or G3KO mice of indicated ages are shown. There were at least 5 mice in each group. C. The percentages (the left two panels) and numbers (the right two panels) of naïve (CD44loCD62Lhi) and memory/effector (CD44hiCD62Llo) cells among lymph node CD8+ T cells of FF and G3KO mice of indicated ages are shown. There were at least 5 mice in each group. D. The absolute numbers of CD8+ T cells and B cells per inguinal lymph node of 6 week-old FF/OT-1 and G3KO/OT-1 mice were counted and shown in the right panel. The percentages (the middle panel) and number (the right panel) of naïve and memory/effector populations among lymph node CD8+ T cells are shown in the right panel. There were 3 mice per group.
