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. 2012 Dec 13;62(1):65–73. doi: 10.2337/db11-1727

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© 2013 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 7. — The effect of growth restriction (IUGR) on glucose production in isolated primary fetal hepatocytes. Hepatocytes were isolated from CON and IUGR fetal livers. Glucose production was measured after 24 h of treatment with 500 nmol/L dexamethasone (DEX), 100 μmol/L cAMP, or 100 nmol/L insulin, as indicated. Results are expressed as glucose produced (μg) per amount of protein per well (μg). Means ± SE are shown (CON cell isolations, n = 4; IUGR cell isolations, n = 4). Significant effects from two-way ANOVA are indicated. *P < 0.05 compared with all other group × treatment (I × T) comparisons.