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. 2012 Nov 30;2:898. doi: 10.1038/srep00898

Figure 2. Sympathectomy of the nervus mesentericus inferior inhibits alpha-synuclein accumulation in the lumbal IML nuclei.

Figure 2

(A-D) Confocal images of thorax superior (A), thorax medium (B), thorax inferior (C) and lumbal (D) fluorescence intensity color-coded images of spinal cord sections stained with rabbit anti-alpha-synuclein or goat anti-ChAT antibodies from SRT mice 4 months after treatment. Scale bar: 20 μm. (E) Quantification of alpha-synuclein MFI rate between ChAT+ and ChAT− areas in different regions of the spinal cord after 2 (n = 8) and 4 months (n = 8) of rotenone treatment. CONT: control, NORT: non-operated rotenone treated and SRT: sympathectomized rotenone treated mice. Values for CONT. 4 months (CONT.4M), NORT 4 months (NORT.4M) and SRT 2 (SRT.2M) and 4 (SRT.4M) months mice are grouped within the thoracic medium (Thorax Med.), thoracic inferior (Thorax Inf.) and the thoracolumbal (Lumbal) regions of the spinal cord. All groups for each region are compared with the CONT.4M group. Error bars represent (s.e.m.) values, n.s. is non-significant, *P<0.05, **P<0.005, ***P<0.001.