Table 1.
Organisms Contained within the Developmental FilmArray BC panel
| Organism | Gene 1 | Gene 2 |
|---|---|---|
| Gram Positive | ||
| Streptococcus pneumoniae | lytA | rpoB |
| Streptococcus agalactiae | sip | |
| Streptococcus pyogenes | speB | |
| Streptococcus spp1 | rpoB | |
| Staphylococcus aureus | nuc | rpoB |
| Coagulase-negative staphylococci2 | rpoB | |
| Enterococcus spp3 | rpoB | |
| Listeria monocytogenes | rpoB | |
| Gram-Negative | ||
| Escherichia coli | gyrB | ompA |
| Klebsiella oxytoca | gyrB | ompA |
| Klebsiella pneumoniae | gyrB | ompA |
| Enterobacter cloacae | gyrB | ompA |
| Serratia marcescens | gyrB | ompA |
| Enterobacteriaceae4 | ompA | |
| Neisseria meningitidis | ctrA | |
| Haemophilus influenzae | rpoB | bexA |
| Pseudomonas aeruginosa | gyrB | |
| Acinetobacter baumanii | tusA | rpoB |
| Yeast | ||
| Candida albicans | ACT | |
| Candida non-albicans5 | RPB-1 | |
| Antibiotic Resistance | ||
| Methicillin | mecA | |
| Vancomycin* | vanA | vanB |
| Carbapenem | blaKPC |
vanC gene included in panel used for the validation study, but subsequently removed.
Streptococcal species included for primer design were: S. pneumoniae, S. parasanguinis, S. anginosus, S. salivarius, S. pyogenes, S. uberis, S. mitis, S. sanguis, S. mutans, S. oralis, S. equinis, S. gordonii, S. gallolyticus
Coagulase-negative staphylococci included for primer design were: S. epidermidis, S. hominis, S. haemolyticus, S. capitis, S. saprophyticus, S. warneri, S. xylosus, S. caprae, S. cohnii, S. koosii, S. saccrolyticus, S. nepalensis, S. microti, S. simiae, S. lugdunensis
Enterococcal species included for primer design were: E. facaelis, E. faecium, E. casseliflavus, E. durans, E. gallinarum
Enterobacteriaceae included for primer design were: E.coli, E. hermannii, E. fergusonii, Shigella sonnei, S. boydii, S. dysenteriae, S.flexneri, C. freundii, Salmonella enterica, S. typhimurium, Enterobacter. aerogenes, E. cloacae, E. sakazaki, Klebsiella. oxytoca, K.pneumoniae, Serratia. marcescens
Non-albicans candida included are: C. parapsilosis, C. glabrata, C. tropicalis, C. krusei