Table 4.
Multivariate analyses (n = 52)
| Wald | pvalue | Hazard ratio | 95% CI | ||
|---|---|---|---|---|---|
|
Progression-free survival (PFS) |
|||||
|
Stage IV disease |
7.805 |
0.005 |
5.52 |
1.665 |
18.285 |
|
High miR-200c |
4.835 |
0.028 |
2.27 |
1.093 |
4.712 |
|
Residual disease (R) status |
5.195 |
0.023 |
4.29 |
1.226 |
14.993 |
|
Overall survival (OS) |
|||||
|
Stage IV disease |
20.469 |
0.000 |
8.60 |
3.385 |
21.831 |
|
High miR-200c |
4.827 |
0.028 |
2.24 |
1.091 |
4.614 |
| Weight loss > 10% | 5.074 | 0.024 | 2.38 | 1.119 | 5.048 |
The levels of miR-200c were considered high when the relative expression level was above the mean. Residual disease (R) was categorised as R0 when no residual disease was present and as R1-2 when microscopic or macroscopic residual disease was found.