TABLE 3.
24 h urinary metabolite excretion in L-Cpr+/+ and L-Cpr mice supplemented with γ- and δ-TOH
| Urinary Metabolitesa |
|||||
| γ-3′-COOH | γ-5′-COOH | δ-3′-COOH | δ-5′-COOH | Total | |
| L-Cpr+/+ | 43.8 ± 4.49 | 37.5 ± 3.11 | 633.3 ± 34.4 | 56.4 ± 8.74 | 771.0 ± 43.9 |
| L-Cpr | 21.5 ± 3.83b | 14.0 ± 3.36b | 166.5 ± 28.5b | 28.3 ± 7.86 | 230.3 ± 41.3b |
| % Reduction | 51% | 63% | 74% | 50% | 70% |
Mice were fed the supplemented diet for 4 weeks. Values represent mean ± SEM (n = 4).
a
nmol/24 h.
b
Significantly different from L-Cpr+/+ mice (P < 0.05). The 3′- and 5′-COOH metabolites of α-TOH were not detected.