Table 4.
Clinical Severity in Respondents with 12-Month DSM-IV/CIDI Bipolar Spectrum Disorders
| BPS | BP-I | BP-II | Subthreshold BP |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| % | SE | % | SE | % | SE | % | SE | χ2* | p-value | |
| Manic/hypomanic episode, %(se) † | ||||||||||
| Severe | 39.6 | 2.7 | 66.6 | 6.3 | 44.3 | 6.2 | 26.6 | 3.3 | 31.2 | 0.000 |
| Moderate | 42.8 | 3.0 | 24.8 | 5.6 | 36.1 | 6.3 | 52.6 | 3.9 | 4.3 | 0.117 |
| Mild | 15.0 | 2.6 | 8.6 | 3.9 | 14.5 | 5.2 | 18.0 | 3.7 | 12.2 | 0.002 |
| None | 2.5 | 0.7 | 0.0 | 0.0 | 5.2 | 2.7 | 2.8 | 0.9 | . | . |
| No. § | 418 | 109 | 72 | 237 | ||||||
| Major depressive episode, %(se) $ | ||||||||||
| Severe | 73.1 | 2.9 | 76.5 | 5.1 | 76.1 | 4.7 | 66.1 | 5.1 | 5.5 | 0.063 |
| Moderate | 25.2 | 2.9 | 20.4 | 5.2 | 22.4 | 4.7 | 33.3 | 5.1 | 2.8 | 0.249 |
| Mild | 1.6 | 0.6 | 3.1 | 1.5 | 1.4 | 1.1 | 0.3 | 0.3 | 1.0 | 0.606 |
| None | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.3 | 0.3 | . | . |
| No. §§ | 416 | 140 | 146 | 130 | ||||||
| Combined, %(se) # | ||||||||||
| Severe | 57.4 | 2.4 | 74.5 | 4.5 | 68.8 | 4.7 | 42.5 | 3.3 | 31.0 | 0.000 |
| Moderate | 33.9 | 2.4 | 21.2 | 4.4 | 26.8 | 4.5 | 44.3 | 3.4 | 7.3 | 0.027 |
| Mild | 7.9 | 1.6 | 4.3 | 1.9 | 4.4 | 2.2 | 11.6 | 2.9 | 7.4 | 0.025 |
| None | 0.8 | 0.3 | 0.0 | 0.0 | 0.0 | 0.0 | 1.5 | 0.6 | . | . |
| No. §§§ | 670 | 192 | 169 | 309 | ||||||
Abbreviations: BPS, bipolar spectrum disorder; BP-I, DSM-IV bipolar I disorder; BP-II, DSM-IV bipolar II disorder; CIDI, Composite International Diagnostic Interview.
Significance tests were performed for cumulative categories. In the case of moderate severity, the BPSsubgroups were compared for the prevalence of severe or moderate vs. mild or none. In the case of mild severity, the BPS subgroups were compared for the prevalence of any severity (ie, severe, moderate, or mild) vs none. No significance test values are given for the final category (none) because of this cumulative coding.
Based on the Young Mania Rating Scale.23
Significant difference across the 3 BPS subgroups at the P=.05 level, 2-sided test.
Number of 12-month cases of mania/hypomania with valid YMRS (New Zealand did not assess the YMRS)
Based on the Quick Inventory of Depressive Symptomatology Self-Report.24
Number of major depressive episodes among people with 12-month BPS with valid QIDS
Respondents who reported both manic/hypomanic and major depressive episodes in the past year were assigned the more severe of their 2 severity scores.
Number of 12-month BPS in the sample with either valid YMRS or valid QIDS.