Figure 4.
DBD-C has an expanded DNA-binding groove that contacts eight contiguous nucleotides. (A) Comparison of DNA-binding grooves and bound DNA from the DBD-A and DBD-C portions of the complex. The L12 and L45 loop segments that mark the sides of the DNA-binding grooves are indicated by arrows. The nucleotides in the two subcomplexes are numbered as in Figure 1B. (B) Rpa–DNA contacts at DBD-C are colored as in Figure 3A. DBD-D of Rpa32 is in pink. Only residues involved in DNA contacts are shown.