Figure 5. Cognitive training during adolescence altered phase synchrony between mPFC sites and between mPFC and hippocampus in adult NVHL rats.
Significant group differences between adolescent trained NVHL and adolescent exposed NVHL rats during the two-frame task. A. Inter-mPFC synchrony: group (F1,30 = 11.27, p = 0.002), frequency (F4,30 = 3.80, p = 0.01), interaction (F4,30 = 0.17, p = 0.95) and B. inter hippocampus-phase synchrony: group (F1,30 = 8.61, p = 0.006), frequency (F4,25 = 2.83, p = 0.04), interaction (F4,25 = 0.29, p = 0.88). C. No significant group difference between adolescent trained NVHL and adolescent trained control rats in inter-mPFC synchrony: group (F1,20 = 2.21, p = 0.15), frequency (F4,20 = 1.55, p = 0.23), interaction (F4,20 = 0.71, p = 0.60) but D. a significant group difference in inter hippocampus-mPFC synchrony: group (F1,10 = 14.48, p = 0.004), frequency (F4,10 = 4.41, p = 0.03), interaction (F4,10 = 0.65, p = 0.64).
