Table 8.
Side Effect Profiles in Patient Receiving Placebo and Pregnenolone
| SYMPTOM | Placebo (n= 9 patients) |
Pregnenolone (n= 9 patients) |
|---|---|---|
| n (%)i | n (%) | |
| Disorientation (date, address, mayor, MD name) |
2 (22%)—mild (both patients) |
2 (22%)—mild (both patients) |
| Decreased interest in sex | 2 (22%)—mild (both patients) |
1(11%)—mild |
| Impaired sexual performance | 2 (22%)—mild (both patients) |
0 |
| Hypertension | 1(11%)—
mild < 145/90) |
1(11%)—mild (< 145/90) |
| Excitation/agitation | 1(11%)—-mild | 0 |
| Dry mouth | 1(11%)—-mild | 1(11%) |
| Malaise | 1(11%)—-mild | 0 |
| Blurred vision | 1(11%)—-mild | 0 |
| Restlessness | 0 | 2 (22%)—mild (both patients) |
| Muscle pain/stiffness | 0 | 1(11%)—mild |
| Cold extremities | 0 | 1(11%)—mild |
| Tremor | 0 | 0 |
| Headache | 0 | 0 |
| Insomnia | 0 | 0 |
| Drowsiness | 0 | 0 |
| Rigidity | 0 | 0 |
| Akathisia | 0 | 0 |
| Diarrhea | 0 | 0 |
| Nasal congestion | 0 | 0 |
| Sweating | 0 | 0 |
| Joint pain/stiffness | 0 | 0 |
| Peripheral edema | 0 | 0 |
| All other side effects | 0 | 0 |