Table 1.
Baseline Demographic and Clinical Characteristics
| Placebo (n= 9) | Pregnenolone (n = 9) | |||
|---|---|---|---|---|
| Male/female | 9/0 | 8/1 | ||
| Age (years) | 49.43 ± 12.19 | 52.68 ±6.31 | ||
| Schizophrenia | 5 | 6 | ||
| Schizoaffective disorder |
4 | 3 | ||
| Caucasian | 3 | 3 | ||
| African American | 5 | 6 | ||
| Other | 1 | 0 | ||
| WRAT | 100.1 ± 15.33 |
101.1 ± 10.94 |
||
| Placebo | Pregnenolone | |||
|
Antipsychotic (mg/day) |
Number
of subjects |
Mean dose ± SD |
Number
of subjects |
Mean dose ± SD |
| Aripiprazole | 1 | 15 ± 0 | 2 | 30 ± 21 |
| Olanzapine | 5 | 18 ± 2.7 | 3 | 13.3 ±7.6 |
| Quetiapine | 1 | 300 ±0 | 2 | 400 ±283 |
| Risperidone | 2 | 5±1.4 | 2 | 6±0 |