Skip to main content
. Author manuscript; available in PMC: 2013 Jul 27.
Published in final edited form as: Mol Cell. 2012 Jul 27;47(2):158–167. doi: 10.1016/j.molcel.2012.06.026

Figure 2. Overview of the interplays between environment, circadian clocks and metabolism.

Figure 2

The circadian clock in the cells comprising metabolic organs, such as liver, functions as an epigenomic programmer and controls metabolic outputs. This autonomous apparatus is regulated by the central clock in the SCN and by food intake via hormones and nutrients/metabolites. Both the central clock and food availability contributes to the temporal regulation of food intake.