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Knockdown of miR-23b expression impairs LN229 tumor growth in vivo. (A) Luminescence imaging for As-miR-23b-treated LN229 tumors vs. scramble-treated controls. (B) Representative photomicrographs of tumor sections following FISH analysis for miR-23b and IH analysis for VHL. (C) miR-23b and VHL expression in intracranial graft assessed by real-time PCR and Western blot (D) β-catenin and HIF-1α expression in tumor sections following IH analysis. *P < .05.
