Fig 9.

ASL hyperperfusion in infiltrative tumor. A 49-year-old woman who presented with seizures had an infiltrative T2 (upper left) hyperintense lesion in the right frontal lobe without significant enhancement on postgadolinium T1-weighted (upper right) imaging (arrowheads). Multivoxel MR spectroscopy (bottom left) reveals an elevated choline/creatine ratio (3:2) consistent with gliomatosis cerebri (yellow arrow). ASL CBF map (bottom right) demonstrates increased signal intensity in the subcortical white matter corresponding to tumor (white arrow).