Table 2.
Effect of lead exposure on brain tissue of CD-1 mice
| GROUP | GSH (nmol/mg pro.) |
GSH/GSSG | MDA (nmol/100mg pro.) |
Glu/Gln | GS (U/mg pro.) |
|---|---|---|---|---|---|
| Control | 14.55± 1.3 | 33.6 ± 7.4 | 15.6 ± 4.1 | 0.88 ± 0.12 | 237 ± 18 |
| Lead only | 11.13 ± 1.3* | 8.7 ± 2.6* | 32 ± 6.3* | 1.66 ± 0.08* | 181 ± 27* |
| Lead + NAC | 13.62 ± 0.7 | 194 ± 21*# | 23.5 ± 1.1*# | 0.76 ± 0.18# | 235 ± 9# |
| Lead + NACA | 15.5 ± 2.0# | 227 ± 33*# | 20.6 ± 2.2# | 0.63± 0.11# | 248 ± 17# |
*
Significance indicated by: p<0.05-0.01 compared to corresponding value of control group;
#
p<0.05-0.001 compared to corresponding value of lead-only group