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. Author manuscript; available in PMC: 2012 Jun 29.
Published in final edited form as: Pharmacogenomics J. 2009 Dec 29;10(5):448–457. doi: 10.1038/tpj.2009.68

Figure 2.

Figure 2

Neutrophil infiltration in COX-1−/−, COX-2−/−, and their WT mice. (a–d) Immunohistochemistry of brain sections with 7/4 antibody. Scale bar, 100 μm. (e) Quantitation of 7/4+ cells showed a significant increase of infiltrated neutrophils in COX-2−/− mice, but not in COX-1−/− mice compared with their respective WT mice. (f) Brain MPO levels were decreased in COX-1−/− mice and increased in COX-2−/− mice compared with their WT controls. Mean±s.e.m. (n = 5–6 per group); *P<0.05, **P<0.01.