Table 1.
Summary of fMRI activity clusters
| Baseline, phobogenic vs. neutral |
Baseline vs. posttherapy |
Posttherapy vs. follow-up |
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| Region (BA) | L/R/B | Volume (mm3) | x | y | z | t | P | t | P | t | P |
| Fig. 1, regions shown in blue | |||||||||||
| Posterior cingulate (BA 31) | B | 8,343 | −4.2 | 36.6 | 40.2 | 1.77 | 0.10 | −2.82 | 0.02 | 2.03 | 0.07 |
| Anterior cingulate/ vmPFC (BA 24, 32) | B | 7,965 | 2.6 | −21 | 24.3 | 3.19 | 0.01 | −3.11 | 0.01 | NS | |
| Anterior insula (BA 13) | L | 2,187 | 51.6 | −8.3 | −1.3 | 2.09 | 0.06 | −2.70 | 0.02 | NS | |
| Anterior insula (BA 13) | R | 1,782 | −36.9 | −6.3 | 5.4 | 3.91 | 0.00 | −2.46 | 0.03 | NS | |
| Posterior insula (BA 13, 19) | R | 8,478 | −46.8 | 43.2 | 14.0 | 2.33 | 0.04 | −2.81 | 0.02 | NS | |
| Middle temporal gyrus (BA 39) | L | 1,134 | 41.2 | 48.9 | 8.6 | 3.77 | 0.00 | −2.71 | 0.02 | NS | |
| Medial frontal gyrus (BA 6) | R | 1,809 | −5.9 | 10.9 | 61.8 | 2.68 | 0.02 | −2.48 | 0.03 | NS | |
| Amygdala (anatomically defined) | R | 891 | n/a | n/a | n/a | 3.65 | 0.00 | −4.59 | 0.00 | NS | |
| Fig. 1, region shown in red | |||||||||||
| dlPFC (BA 6, 8) | R | 918 | −35.6 | −17.2 | 55.1 | −2.38 | 0.04 | 8.27 | 0.00 | −2.63 | 0.02 |
| Superior parietal lobule (BA 7) | R | 1,458 | −24.5 | 66.8 | 55.8 | NS | 3.12 | 0.01 | NS | ||
| Fig. 2, regions shown in gray | |||||||||||
| Fusiform/lingual gyrus (BA 18, 19) | L | 8,046 | −34 | −81 | −9 | 4.91 | 0.00 | NS | −5.10 | 0.00 | |
| Fusiform/lingual gyrus (BA 18, 19) | R | 11,367 | 36 | −78 | −11 | 5.14 | 0.00 | NS | −5.36 | 0.00 | |
For each activity cluster, listed are Brodmann areas (BA), hemisphere [left (L), right (R), or bilateral (B)], the volume (mm3), and stereotactic coordinates for the centrally activated voxel (x, y, z mm). Statistics are reported for all P values ≤ 0.10, and otherwise listed as nonsignificant (NS).