TABLE 1.
The largest and best characterized ferritin-like protein families
Ferritin-like proteins can be broadly characterized into four functional categories: iron storage, reactive oxygen species (ROS) protection (in which we include biotic oxidation of Fe(II)), substrate oxidation, and radical generation. Dashes are used where corresponding groups are not found in a classification scheme.
| Protein | Abbreviation | Functional category | Metals | References |
|---|---|---|---|---|
| Ferritins | Ferritins | Iron storage | Fe2 | Ref. 48 |
| Bacterioferritins | Bacterioferritins | Iron storage | Fe2 | Ref. 48 |
| Dps | ROS protection, iron storage | Fe2 | Ref. 49 | |
| Manganese catalases | Manganese catalases | ROS protection | Mn2 | |
| Fatty acid desaturases | Fads | Substrate oxidation (introducing a double bond) | Fe2 | Ref. 50 |
| Bacterial multicomponent monooxygenases | BMMs | Substrate oxidation (e.g., methane, phenol and other aromatic compounds) | Fe2 | Ref. 27 |
| Class I ribonucleotide reductase radical generating component | RNR R2s | Radical generation | Fe2, Mn2, or MnFe | Ref. 25 |