Figure 6.
Influenza infection increased microglia reactivity. A, Influenza infection increased the proportional area of Iba-1 staining in the hippocampus at day 7 after infection. B, Influenza infection increased the number of Iba-1-positive cells in the hippocampus at day 7 after inoculation. C, D, Representative examples of Iba-1-positive cells in the dentate gyrus of a control (CON, C) and influenza-infected (FLU, D) animal. Inset includes enlarged image of Iba-1-positive cell indicated by arrow. Magnification = 40×; scale bar, 50 μm. Data are represented as means ± SEM (*p < 0.05, **p < 0.01, #p = 0.08 compared with controls).