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. Author manuscript; available in PMC: 2012 Oct 13.
Published in final edited form as: Mol Cell. 2012 Mar 8;46(1):67–78. doi: 10.1016/j.molcel.2012.02.005

Figure 4. Loss of Glmn Leads to Decreased Levels of Rbx1 and Cullins and Increased Abundance of Cyclin E.

Figure 4

(A) Lysates from E9.5 Glmn+/+, Glmn+/− and Glmn−/− embryo and yolk sac were WB.

(B) Relative mRNA levels for indicated genes in Glmn+/+, Glmn+/− and Glmn−/− embryos. Results are shown as means ± standard error, calculated from three independent experiments.

(C) Sections of Glmn+/+ and Glmn−/− placentas at E9.5 were stained with Cyclin E antibody (200x).

(D) Lysates from U-2OS cells transfected with Glmn, Rbx1 or control siRNA were WB.

(E) Extracts from Glmn+/+ or Glmn−/− ES cells stably expressing HA-Glmn, HA-m-d393, or EV were WB.

See also Figure S2