FIGURE 8.
SU5416 and indomethacin are both capable of blocking suppressor endothelial cell-mediated disruption of T-cell proliferation. T-cell proliferation responses to immobilized anti-CD3 in the presence of endothelial cell-conditioned media were measured by MTS. Statistics shown are Student t test results between indicated treatment groups. Data shown are mean ± SD with n ≥6 mice per treatment group from 2 separate experiments. MTS indicates 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium. INDO, indomethacin.