Fig. 3. Expression of tau phosphorylated at S396 in mouse hippocampus.
Hippocampus from 24-week old male db+ (panel B) and db/db (all other panels) mice was harvested for immunofluorescent staining of tau phosphorylated at S396 (red), NeuN (green), CD11b (green), GFAP (green) and MAP2 (green). Both db+ and db/db mice did not receive any injections. NeuN and MAP2 are proteins expressed in neurons. CD11b and GFAP are proteins expressed in microglia and astrocytes, respectively. An arrow in panel A indicates positive staining for tau phosphorylated at S396. The bar represents 200 μm in panels A and B and 20 μm in other panels (panels C to N).
