Table 3.
Differential expression of HIF1α target genes in HIF1α−/− LSCs comparing to HIF1α−/− normal HSCs
| Symbol | Gene name | Relative fold change, Log2 |
|---|---|---|
| c-MET | Met proto-oncogene | −0.2 |
| KRT18 | Keratin 18 | −0.26 |
| Hmox1 | Heme oxygenase-1 | 0.67 |
| MMP2 | Matrix metallopeptidase 2 | 0.74 |
| UPAR | Urokinase-type plasminogen activator receptor | 3.1 |
| ETS1 | E26 avian leukemia oncogene 1 | −1.8 |
| Nr4a1 | Nuclear receptor subfamily 4, group A, member 1 | −0.27 |
| VEGF | Vascular endothelial growth factor A | 1.3 |
| Glut1 | Glucose transporter 1 | 3.4 |
| TGFα | Transforming growth factor alpha | 0.52 |
| Trf | Transferrin | −5.4 |
| P4ha1 | Prolyl 4-hydroxylase, alpha polypeptide I | −2.8 |
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.77 |
See Table 1 for expansion of abbreviations.