Figure 5. Ablation of FAK affects trastuzumab sensitivity.
A) BT474 cells, transfected with siRNA’s, were plated on A) laminin-5 (1 × 104 cells/well) or B) non-coated plastic, treated with trastuzumab for 2 days, and cell numbers were assessed. C) Efficiency of FAK and CD151 knockdown was determined by immunoblotting.
