Figure 1. Procrustes analysis shows that mammalian bacterial lineages and metagenomic gene content give similar clustering patterns.
(A) Cartoon illustrating Procrustes analysis. The Procrustes transformation of the blue and red data types (i) results in a good fit, while the transformation of the green and red data (ii) yields a worse fit with large distances separating data from samples B and C. (B–E) Procrustes analysis of 16S rRNA sequences (weighted UniFrac) against KEGG Orthology (KO) groups, CAZymes (glycoside hydrolases), peptidases, and E.C.s. Every sphere represents a single mammalian fecal community and is colored by host diet. The black end of each line connects to the 16S data for the sample, while the orange end is connected to the functional annotation data. The fit of each Procrustes transformation over the first three dimensions, is reported as the M2 value.
