Table 3.
Results of IHC Stainings on Tissue Microarrays
| Protein | Location of staining | Normal | Negative | Weak | Moderate | Strong | |
|---|---|---|---|---|---|---|---|
| cDNA array, cluster I gene-encoded | ANG | Cytoplasm + Stroma | (+) | 17 | 19 | 5 | 14 |
| BCL2 | Cytoplasm | (+) | 23 | 10 | 17 | 5 | |
| ESR1/ER | Nucleus | (+) | 22 | 14 | 5 | 14 | |
| GATA3 | Nucleus | (+) | 26 | 12 | 7 | 10 | |
| MUC1 | Cytoplasm | (+) | 3 | 19 | 8 | 25 | |
| THBS1 | Cytoplasm + Stroma | (+) | 16 | 30 | 9 | 0 | |
| cDNA array, cluster II gene-encoded | MLANA | Cytoplasm | (+) | 22 | 20 | 6 | 7 |
| PRLR | Membrane | (+) | 21 | 12 | 7 | 15 | |
| Others | CDH1 | Membrane | (+) | 6 | 10 | 14 | 25 |
| ERBB2 (CB 11) | Membrane | (−) | 34 | 14 | 4 | 3 | |
| ERBB2 (AO485) | Membrane | (−) | 30 | 11 | 9 | 5 | |
| ERBB2 (3B5) | Membrane | (−) | 37 | 8 | 2 | 8 | |
| FGFR1 | Membrane + Cytoplasm | (+) | 20 | 20 | 12 | 3 | |
| Ki67 | Nucleus | (+) | 4 | 27 | 13 | 11 | |
| P53 | Nucleus | (−) | 33 | 12 | 0 | 10 | |
| TACC1 | Cytoplasm | (+) | 21 | 22 | 9 | 3 | |
| TACC2 | Cytoplasm | (+) | 5 | 18 | 13 | 19 |
(+) and (−) mean expressed or not in normal breast tissue, respectively.