. 2011 Jun 30;6(1):31–45. doi: 10.1038/ismej.2011.83

Table 4. Sinus isolates from several patients display mutations and phenotypes associated with poor lung disease prognosis.

	SCVa	Loss of Las QS signalsb	Mucoid (mucA⁻)	Reduced or loss of motilityc
No. of patientsd	4	2	2	6

Abbreviations: SCV, small colony variants.

A morphotype was classified as a SCV when it displayed characteristics as previously described for SCVs: small colony morphology, clumping in liquid culture and greatly enhanced biofilm formation (Haussler et al., 1999, 2004).

Only one of the two patients had lost production of 3-oxo-C12-HSL molecules owing to mutation in lasR.

Minimum one sinus morphotype had lost or was significantly reduced in swimming and twitching motility.

No. of patients out of the six sinus colonized patients.