Table 1.
Selected DEGs for KC sorted vs. KC LCM
| Gene | mRNA | Description | FCH a, b |
|---|---|---|---|
| IL1RL1 | IL-1RL1 | interleukin 1 receptor-like 1 | 2659.0 |
| MMP1 | MMP-1 | matrix metallopeptidase 1 (interstitial collagenase) | 2014.7 |
| IL8 | IL-8 | Interleukin 8 | 2004.5 |
| CCL20 | CCL20 | chemokine (C-C motif) ligand 20 | 1909.2 |
| MMP3 | MMP-3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 1296.4 |
| KRT6B | KRT6B | keratin 6B | 883.4 |
| AREG | AREG | amphiregulin | 430.9 |
| HBEGF | HB-EGF | heparin-binding EGF-like growth factor | 341.5 |
| CXCL2 | CXCL2 | chemokine (C-X-C motif) ligand 2 | 322.8 |
| KRT6A | KRT6A | keratin 6A | 217.9 |
| S100A9 | S100A9 | S100 calcium binding protein A9 | 187.5 |
| CXCR4 | CXCR4 | chemokine (C-X-C motif) receptor 4 | 176.1 |
| S100A8 | S100A8 | S100 calcium binding protein A8 | 129.1 |
| CXCL3 | CXCL3 | chemokine (C-X-C motif) ligand 3 | 123.1 |
| CXCL1 | CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 59.3 |
| S100A7 | S100A7 | S100 calcium binding protein A7 | 57.4 |
| STAT3 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 51.3 |
| RNASE7 | RNase 7 | ribonuclease, RNase A family, 7 | 47.9 |
| LCN2 | NGAL | lipocalin 2 | 40.6 |
| IL1F9 | IL-1F9 | interleukin 1 family, member 9 | 35.6 |
| PI3 | elafin | peptidase inhibitor 3, skin-derived | 35.5 |
| IL1R2 | IL-1R2 | interleukin 1 receptor, type II | 31.1 |
| TNF | TNF | tumor necrosis factor | 25.9 |
| IL20 | IL-20 | interleukin 20 | 22.2 |
| IL1A | IL-1α | interleukin 1, alpha | 18.6 |
| TGFA | TGF-α | transforming growth factor, alpha | 16.5 |
| IL15 | IL-15 | interleukin 15 | 8.8 |
| IL23A | IL-23A | interleukin 23, alpha subunit p19 | 8.7 |
| IFNK | IFN-κ | interferon, kappa | 6.6 |
| HLADQB2 | HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 | − 111.1 |
| HLADPA1 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | − 83.3 |
| PNPLA3 | PNPLA3 | Patatin-like phospholipase domain containing 3 | − 66.7 |
| CD1A | CD1A | CD1a molecule | − 58.8 |
| CD207 | CD207 | CD207 molecule, langerin | − 50.0 |
| HLADPB1 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 | − 50.0 |
a
FCH = Fold-change in gene expression
b
FDR < 0.01 for all genes