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Means±S.E.M. protein levels in whole brain lysates from 52–60-week-old WT, NOS2−/−, APPSw and APPSw/NOS2−/− mice were measured using standard ELISA assays (n = 5–7 mice per strain). *P<0.05, ***P<0.001 compared with the NOS2−/− or WT control mice. ###P<0.001 compared with the parent strain.
