Figure 2.
Comparison of the power of four methods for eQTL mapping when the MAF of the target SNP is 0.05 (a) or 0.2 (b). P-value cutoff of 0.05 is used to call significance and power is calculated as the percentage of simulations where the p-values are smaller than 0.05, among 2,000 simulations. The horizontal dash line at the bottom of each figure corresponds to a power of 0.05. When the fold change is 1.0, all methods’ power is approximately 0.05, which indicates that type I errors are controlled at a desired level by all methods.