Figure 1. Relationship between outcome and age of participants in studies of cholesterol’s effect on dementia risk and progression.
For each balloon, the left-most end is positioned at the mean age at study start, the width represents the follow-up time, and the height represents the cohort size. Red color signifies a positive correlation between cholesterol levels and dementia risk, gray a negative correlation, and blue no correlation. An additional study by Whitmer and colleagues7 is not included here because the large size of its cohort and long follow-up period would distort the figure.
