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. 2011 Nov 4;6(11):e27283. doi: 10.1371/journal.pone.0027283

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Armand et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Quantification of fibers expressing type I, type II, embryonic and neonatal MyHC in WT and Hq soleus (A, C, E, G) and EDL (B, D, F, H) muscles 3 (A, B), 5 (C, D), 10 (E, F) and 20 (G, H) days following cardiotoxin injury indicates a slow fiber type switch and an increase in immature regenerating myofibers in Hq mice, the latter corroborating the delay in skeletal muscle regeneration of Hq mice. * indicates P<0.05 vs WT.