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Cell survival and BiP/GRP78 gene expression after R-CHOP-BZ combination. A: R-CHOP-BZ overcomes primary resistance to bortezomib in all DLBCL cell lines and increased cell death associated with R-CHOP in all cell lines but in SUDHL-6. B: R-CHOP and R-CHOP-BZ significantly reduced BiP/GRP78 mRNA expression in all cell lines. Error bars represent 2 SDs.
