Figure 5.
Pharmacogenetics of FAAH and colonic motility index. Differential treatment effects among FAAH rs324420 genotypes (CC vs. CA/AA) and IBS subtypes were observed for proximal left colon MI, (p=0.09), and were most pronounced in IBS-D/A and CA/AA (p=0.013). Differential treatment effects were also observed for distal left colon MI (p=0.046), and were most pronounced in IBS-C and CC (p=0.045). Data reported are least squares (LS) means and standard errors (SEM). The error bars are based on the square root of the ratio: pooled estimate of residual error variance (across all subgroups from the ANCOVA) divided by the subgroup sample size.