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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: J Immunother. 2011 Oct;34(8):569–580. doi: 10.1097/CJI.0b013e31822b5b1d

Table 1. Predicted HLA-A2 affinity and homology of Human and Mouse SSX-2 nonamer peptides.

Shown are the peptide names, amino acid sequences, and predicted HLA-A2 affinity scores of potential HLA-A2 peptides derived from the amino acid sequence of human SSX-2, as well as the respective murine Ssxa1 and Ssxb1 peptide sequences and binding affinities. Predicted HLA-A2 peptide affinity was determined by scanning the SSX-2, Ssxa1, and Ssxb1 protein sequence with two different peptide prediction algorithms [29, 30]. A known HLA-A2-binding peptide derived from the influenza A matrix protein is shown for comparison [39]. Amino acids within the mouse peptide sequences shown in gray represent identical peptide residues between the human and murine peptides.

Human SSX-2 Peptide Name Peptide Sequence Predicted Binding Affinity [BIMAS] Predicted Binding Affinity [SYFPEITHI] Mouse Peptide Homologue (Ssxa1 Ssxb1) Predicted Binding Affinity [BIMAS] Predicted Binding Affinity [SYFPEITHI]

SSX2p16 QIPEKIQKA 6.4 21 graphic file with name nihms315052t1.jpg 0.001 8
1.022 12

SSX2p20 KIQKAFDDI 4.7 17 graphic file with name nihms315052t2.jpg 0.010 9
2.726 16

SSX2p41 KASEKIFYV 1017.1 22 graphic file with name nihms315052t3.jpg 0.501 19
321.9 14

SSX2p57 AMTKLGFKA 20.8 16 graphic file with name nihms315052t4.jpg 3.588 13
205.9 23

SSX2p99 MTFGRLQGI 2.1 20 Deleted - -

SSX2p103 RLQGISPKI 10.4 23 Deleted - -

SSX2p167 RLRERKQLV 21.7 22 graphic file with name nihms315052t5.jpg 21.672 22
0.029 19

Influenza GILGFVFTL 550.9 30 N/A - -