Figure 8.
Injection of proteasome inhibitors into Xenopus blastomeres blocks centrosome duplication. Animal pole cells from frog embryos were injected with DMSO alone (solid bars) or DMSO containing CLBL (hatched bars), and with FITC-conjugated dextran and subsequently incubated in cycloheximide, fixed and stained with antibodies to α-and γ-tubulin. Centrosomes in individual injected cells were counted and the data represented in histogram form.
